My doctor prescribed me Zoloft and asked me to call him in a couple of weeks to tell how things are going with the meds. The recent problem I've been having is lack of sleep. I was taking the medication late in the morning because I have to wake up early to get to work and I thought it was better to take the medication with food and around the same time each day. On the weekends I get up late in the morning and then take the meds. I was told taking the medication earlier would be better for better sleep and it was okay to take the meds at a different time on the weekends. Anyone else taking meds on different days and times of the week? Thanks for your help!